In 1969, the Airstream trailer had its first major redesign in over 30 years, with an internal facelift as well as exterior and structural changes. The end result was an Airstream with rounder edges and more streamlined shape, a more luxurious and comfortable interior, and a more distinct "bullet" shape. It even added a foot of length and four inches of width. It was a big step on the path from Wally's first trailer to the one you see on the road today.
When humans first visited the moon in 1969, it was feared that the astronauts who walked on its surface might bring back disease or other maladies with them. NASA took every precaution, and it was decided that the Apollo 11 trio would be quarantined upon their safe return. Airstream was tasked with constructing a "mobile quarantine unit" that could be taken to the USS Hornet, which would greet Neil Armstrong, Buzz Aldrin, and Michael Collins. There's even a famous photo of President Richard Nixon speaking to the trio from outside.